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Cartrophen Vet

Cartrophen Vet

Pentosan Polysulphate 100mg/ml.
Cartrophen Vet is a DMOAD (Disease Modifying Osteoarthritis Drug)

Target Species
Dogs.

Indications for use.

UK: For the treatment of lameness and pain of degenerative joint disease/osteoarthrosis (non-infectious arthrosis) in the skeletally mature dog.

IE: For the treatment of lameness and pain of osteoarthritis (non-infectious arthrosis) and related musculoskeletal disorders by therapeutic activity on the underlying pathological processes (disease modifying osteoarthritis drug) in the dog.

Species: Dogs
Active(s): Pentosan Polysulphate 100mg/ml
Pack Size: 10ml
Legal Category:  UK: POM-V; IE: VPO

UK SPC:  http://www.vmd.defra.gov.uk/ProductInformationDatabase/Search.aspx

IE SPC: https://www.hpra.ie/homepage/veterinary

Category: Companion Animal
  • Description
  • Brand

Description

DMOAD Actions
The PPS in CARTROPHEN VET has been shown to exhibit the following actions:

  • Improve the quality of cartilage – Stimulates chondrocytes to synthesize cartilage matrix
  • Improves the quantity and quality of synovial fluid – Stimulates synoviocyte biosynthesis of hyaluronan, improving both the quantity and molecular weight
  • Reduces the levels of cartilage degrading enzymes – Metalloproteinase (as collagenase) and elastase are significantly reduced and tissue inhibitor of metalloproteinase (TIMP) is increased
  • Stimulates stem cell activity and cartilage cell differentiation – Promotes mesenchymal precursor cell (MPC) proliferation and cartilage cell differentiation. Importantly, the frequency of MPCs is elevated in OA cartilage
  • Increased blood supply and nutrition to the joint and subchondral bone – Mobilizes thrombi and fibrin deposits, lipids and cholesterol in both synovial tissues and subchondral blood vessels
  • Strong anti-inflammatory properties – The potent anti-inflammatory activities of PPS have been consistently demonstrated in different models of severe inflammation
  • Eliminates free radicals – Stimulates the release of the free radical scavenging enzyme, superoxide dismutase (SOD)
  • Stimulates important growth factors that promote cartilage growth – Increases the production of the essential trophic factor for cartilage, insulin- like growth factor-1 (IGF-1)11, which stimulates incorporation of sulfate and encourages cartilage growth
  • Affinity for cartilage –The strong binding of the drug to cartilage protein results in therapeutic concentrations for 4 days

Brand

Cartrophen

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HEAD OFFICE (IRELAND)

Block 3, Unit 9,
CityNorth Business Campus,
Stamullen, Co. Meath,
K32 D990
Ireland.

CONTACT US

Sales & other enquiries
Email: enquiries@fortehealthcare.com
Ph: IE +353 (0)1 841 7666  UK+44(0)1 292 800013
Technical Enquiries: vets@fortehealthcare.com

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